Search on: VITAMIN K-DEPENDENT PROTEIN S 
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Descriptor English:   Protein S 
Descriptor Spanish:   Proteína S 
Descriptor Portuguese:   Proteína S 
Synonyms English:   Vitamin K-Dependent Protein S  
Tree Number:   D12.776.124.670
D12.776.395.642
D23.113.725
Definition English:   The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis. 
Indexing Annotation English:   a blood protein; an anticoagulant
Pharmacological Action:   Anticoagulants
 
Entry Combination - descr/qualif English:   Protein S/deficiency use Protein S Deficiency
 
History Note English:   93; was PROTEIN S, VITAMIN K-DEPENDENT (NM) 1979-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30593 
Unique Identifier:   D017293 

Occurrence in VHL: 		 

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